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Revisiting Low Dose Naltrexone For Fibromyalgia Symptoms

Does does Low Dose Naltrexone work on Fibromyalgia symptoms, and if so, why?

It is time for revisiting Low Dose Naltrexone for Fibromyalgia symptoms. LDN is a medication that works to block opioid receptors in the brain for a short time during the night. As the drug wears off, the ‘uptake’ causes the body to produce more endorphins and dopamine, to compensate for the ‘down’ time.

The shortage of endorphins produced in Fibromyalgia and many auto-immune diseases, are believed to be a major reason for the triggering of flares, even the possibility of the onset of the disease itself. LDN is being shown to be a type of wonder drug where HIV/MS/certain cancers/Fibromyalgia/Parkinsons ect. is concerned.

Low Dose Naltrexone is showing to be a 'wonder drug' for many with various autoimmune diseases~ Click To Tweet



When I have written a post on this subject before, I inevitably get the comment/question having to do with the fact that Naltrexone is used for drug addicts and/or alcoholics. Followed by the comment/question as to why am I advocating its use in FMS, and why do I say there are few side effects when Naltrexone actually has some very serious side effects?
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So here is the scoop. Yes, ‘Naltrexone’ is used for treatment in opioid abuse, heroin addiction, and alcoholism. When treating these conditions, a high dosage of Naltrexone is used. What is prescribed in the treatment of FMS and other auto immune disorders is a low dosage of  Naltrexone. For addiction treatment 50 mg is used daily, as opposed to 1.5 – 4.5 mg used only at night by FMS patients. In the high dose there can be some major side effects (albeit, compared to heroin addiction, some choose to take their chances). However, with the very low dose given for treatment of FMS symptoms, the side effects are unbelievably minimal.

Revisiting Low Dose Naltrexone For Fibromyalgia Symptoms

Revisiting Low Dose Naltrexone For Fibromyalgia Symptoms

Affects endorphin production ~ usually related to mood, endorphins also play a role in pain relief, immune system regulation, and growth of cells.

Very inexpensive ~ cost ranges from $30-$40 a mo.

Compound Pharmacy ~ LDN is not mass-produced by chemical companies (why it remains cheap and relatively unknown). It is made by specific ‘compound’ pharmacies in the country. Buy ONLY from these pharmacies in order to avoid less pure products made with ‘fillers’ or are ‘slow release’. It is important to get the full dose all at once in order to reap its benefits.

Possible Help With Opioid Attainment Difficulty ~ We all know about the war on opioid use by the current administration, and the disastrous effects it is having on the chronic pain community. When using LDN you cannot be simultaneously using an opioid pain reliever (obviously since LDN blocks the opioid receptors), so use of LDN to help restore natural pain relief in the body could help.

LDN helps the body to restore natural pain relief ability~ Click To Tweet

I have FINALLY contacted my doctor to call in the prescription to get the ball rolling. Since hearing about LDN last year, I have been eager to try it. It seems to work on approx. 70% of the people who use it, with claims of about a 30-40% reduction in FMS related symptoms. Stay tuned for further updates!


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  • Reply
    November 8 at 11:38 am

    I am very interested on how this goes for you. I haven’t done it yet for 2 reasons: 1) You need to stop taking Norco for 3 days before starting the LDN. 2) It usually takes up to one month before you find out if it works for you. This would be very difficult for me with the stressors in my life. I’m hoping to take some time off and/or maybe work part-time and file for disability for that first month. I work full-time at an office and couldn’t function without something. So, I look forward to your follow-up.

    • Reply
      November 8 at 12:48 pm

      Me too Julie! I’ve known several people who say it is one of the only things that works for them. I’ll keep everyone updated! 🙂

  • Reply
    November 9 at 9:28 am

    I went to my doctor today and asked to try it. He was surprised I knew about it and says he has had very good results. I will let you know

    • Reply
      November 9 at 11:02 am

      So cool Kathy!! I’m really excited about this! Remember it has a cumulative effect, so it will take time to build up. Let me know how it goes! Good luck! 🙂

  • Reply
    November 17 at 8:38 pm

    Kristine, when I first read about this I wondered about its use for addicts. My son is an opiate addict, and he began taking opiates because his neurotransmitters were not working correctly and he wasn’t getting dopamine to ease his depression. And once his bipolar symptoms ramped-up this helped him stay in control. At least for a bit. Obviously taking opioids in any form, that are not prescribed to you, is extremely dangerous. He is now taking Suboxone to help retrain his neurotransmitters as he is stepped down in the medication. I know that he said that it is a great pain reliever. I hope that it works for you. Keep us updated.
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    • Reply
      November 18 at 9:45 am

      Thank you so much NIkki. Hope your son is doing well. ♥ to you!

  • Reply
    Kim Olin
    December 7 at 7:38 pm

    I was in to see my doctor today. I was there to talk about Suboxone for chronic pain & fibromyalgia. Ha said since my pain isn’t “significant” enough to warrant its use, but did recommend LDN. I was on a boat load of Benzo’s so don’t want to go on anything to mess my head up again.

    • Reply
      December 7 at 9:46 pm

      I understand your concern Kim. Do some research on LDN. I have not come across anyone yet who had problems re mental issues. It will probably give you vivid dreams for awhile, but my emotions have actually evened out, as well as an increace in my sense of well-being in the short time I have taken LDN. There are a few private groups on FB I encourage you to join. You can ask questions or just read what others are experiencing. This website is an excellent resource of information as well: Good Luck to you Kim! 🙂

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